Does a boss emerge in the third act? In the confines of Utzaal, Napuatzi unleashes a dizzying array of toxic attacks within a remarkably compact environment, trapping you in a disorientingly tight combat space.
While Viper Napuatzi may not boast the complexity or intensity of some battles in Acts 2 and 3, her confined environment and expertise with poison render her a formidable opponent. When she unleashes a flurry of devastating attacks in rapid succession, she can envelop the environment in a deadly cloud of poison or trap her foes in a precarious corner.
Our comprehensive guide provides valuable insights and practical strategies to prepare for battle and successfully navigate the challenges that arise from the onslaught of attacks you’ll encounter.
The viper Napuatzi’s vulnerabilities and simple strategies for construction are as follows:

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When battling the Viper Naputazi boss, you’ll likely wish to level up and be well-prepared. Tragically, alongside warmth, coldness, and electrical storms. With a simple glance, she can render herself impervious to physical injury. Since you’re aware of this reality, you may consider leveraging the resources readily available to you at this juncture or strive to breach her defenses to the maximum extent possible.
Courses that focus on melee combat become significantly more practical when compared to their magical counterparts, such as the Warrior with its devastating slam attacks, or the Witch who can now summon chaotic constructs at this stage. The ranger equipped with poison or chaos-based assault abilities can prove surprisingly effective. Courses with inherent difficulties, like the Monk or Sorceress, necessitate strategic stacking of gear and protection, particularly prioritizing chaos resistance. As poison damage falls under the chaos harm category, it’s crucial to account for this when building a resilient character.
The primary means of taking action lies in utilizing farming gear with chaotic resistance statistics throughout Act 3. Utilizing the Passive Talent Tree’s highway system, navigate to acquire chaos resistance nodes strategically placed throughout the tree, potentially requiring detours from your initial path.

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You can also equip a chaos resistance ring, available as a random drop throughout Act 3 or purchased from various vendors in Acts 2 and 3.
When you’ve successfully defeated Ignagduk – a milestone likely achieved after dedicating time to cultivating your Spirit – and fulfilled the requirements of the Tribal Vengeance quest, you’ll unlock the option to select the coveted Blooming Antidote Allure. This ability grants you immunity to poison, rendering you unaffected by poisonous attacks once activated. If you haven’t selected it, your sole hope is to stumble upon it by chance while farming enemies at random.
To emerge victorious against the formidable Viper Napuatzi in Path of Exile 2, you must first master her unique abilities and exploit her weaknesses. Start by equipping a well-rounded build that combines elemental damage with physical harm. Next, develop a keen understanding of her movement patterns and use this knowledge to dodge her attacks effectively. Timing is crucial when facing Viper Napuatzi; ensure you’re always one step ahead by using your surroundings to your advantage.
In Viper Napuatzi, the player faces a challenging combat experience within a confined environment where multiple visual elements converge, creating an intense and dynamic atmosphere. Throughout the battle, her attacks will accumulate incrementally, rather than switching between separate stages. As the battle rages on, her behavior becomes increasingly erratic. As follows, we will dissect each assault in the sequence they appear.
The primary arsenal of attacks wielded by Viper Napuatzi features a diverse range of spear-based strikes. This feature incorporates a lunging attack, potentially evadable by sidestepping or moving towards it, paired with a standard three-hit combination. Two primary attacks strike simultaneously, followed by a swift advance and a powerful thrust of the spear that amplifies her next move’s effectiveness with a third decisive strike. To successfully dodge these attacks, roll away from her during the initial two assaults and subsequently avoid the slam by rolling to the side.

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As she advances cautiously, the tip of her spear describes slow arcs through the air. As she prepares to attack, she will surge forward, swiftly spinning her spear while inflicting toxic damage. To avoid the impending attack, swiftly sidestep out of harm’s way. Most attacks she unleashes will inflict a debilitating combination of poison and chaotic damage, ensuring that any successful strike is followed by a prolonged period of harm as the victim succumbs to the toxic effects. That’s why chaos harm resistance is crucial, as acquiring some can prove vital.

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As she approaches, she swiftly sprints towards you, moving with a determination that closes the distance between you in an instant. As Napuatzi grips the spear with precision, its true nature reveals itself: the deadly point now radiates a subtle yet potent aura of poisonous energy. As the battle intensifies, a thunderous audio cue resounds through the air, preceding a devastating ranged attack. With calculated precision, she unleashes a dual-pronged assault, summoning not one, but two serpentine projectiles to hurtle forth from her vantage point. As its global presence is considerable, it’s essential to avoid confrontation by distancing oneself when she unleashes her fully charged attack. As she charges ahead, she’ll loudly proclaim her intent to assault? As soon as she comes to a halt, prepare yourself to deflect any incoming attacks.

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As she prepares to attack again, she executes a swift retreat, followed by a calculated toss of poison that necessitates a hasty backward dodging maneuver from your end. As a result, she unleashes a barrage of lightning-fast knives that ricochet off the boundaries of reality itself. You’ll be able to dodge attacks by rolling away from them effectively using the assault’s aspect.
To successfully navigate these assaults, you’ll need to employ a mix of auto-targeting single-target abilities, area-of-effect spells, and projectiles such as partitions and orbs while opportunistically using dodges to avoid taking damage. Keep a respectful distance from her at all times. Information flows gradually across the environment from a moderate distance, maintaining a consistent medium-range proximity. By mastering effective dodges, you’ll be well-equipped to avoid the majority of her close-range attacks, allowing you to focus on other strategies without worrying about incoming projectiles.
When playing a Warrior or melee-focused class, it’s crucial to specialize in abilities such as totems and shockwaves. As long as you don’t overexert yourself, Napuatzi’s vitality shield will replenish itself.

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As Napuatzi’s health declines to approximately 85%, she will then position her spear on the ground, surrounding its base with a toxic pool. Can she summon elemental forces to suspend her body mid-air, unleashing devastating aerial attacks that rain down upon the earth? Marked by circles on the bottom, these obstacles require a strategic approach to avoid. The key to success lies in moving deliberately and cautiously across the environment, taking small steps to navigate around them safely. Don’t roll. Redirecting efforts to zones where bombardments have spared them (or have merely touched)?

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She will reinforce this upheaval with chaotic barrages that achieve the same effect. The realm of influence for these effects is significantly broader, necessitating a willingness to roll and dodge with purpose. Fortunately, there are significantly fewer instances of rapid bombardments compared to those that occur at home. Despite this, you will still need to walk through vacant regions ravaged by war, or areas where recent bombardments have left their mark.
As Napuatzi touches down for a second time, she unleashes a barrage of toxic projectile spheres that can inflict significant damage. With precision-crafted unpredictability, these venomous orbs can manifest as either rapid-fire barrages of toxic darts or as a concentrated salvo of five or six projectiles, all hurtling towards her with calculated menace. To effectively counter this opponent, focus on sustained area-of-effect damage, as attempting prolonged spellcasting or melee attacks will be futile given the constant formation shifts.
As a shotgun blast hurtles towards you, swiftly roll into an assault position to dodge the projectile; meanwhile, exploit the opportunity to circle around Napuatzi and safely navigate clear of the toxic projectile stream. As she prepares to swiftly modify guidelines, her goal is to capture every possible aspect; therefore, it is crucial that you endeavour to manage her effectively. If she’s lucky enough to land by her spear after surviving the barrage, she might choose to swap out her projectiles for close-quarters combat once more.

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However, Napuatzi’s slow-moving poison projectiles require no initial dodging, as they are easily sidestepped or evaded. Despite this, projectiles launched during her subsequent attacks linger in the environment for a brief period.
When she prepares to launch into an aerial attack, swiftly retreat to avoid her impending slam strike by jumping into the air and screaming while it’s happening. When Nautuzi lowers herself into a crouched position, she’s poised to deliver one of her most formidable and debilitating attacks. As she periodically unleashes small, sluggish venomous projectiles, she will momentarily retreat beneath the surface before re-emerging to unleash a barrage of spears from her minion minions, which create a formidable barrier across the environment.
The minions will periodically hurl spears back and forth, momentarily emitting a radiant green glow before striking, allowing you to anticipate their attack and either dodge or position yourself outside of their line of fire. You must carefully manage both flanks, as the enemy may launch a surprise attack from either direction.

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To successfully employ this tactic, maintain a safe distance from the enemy’s stronghold at Napuatzi while employing a zigzag pattern of movement, constantly adjusting your position in response to the minions’ assault, using their movements as a guide. After concluding the assault, Napuatzi will revert to employing the remaining moves outlined earlier. Moreover, each time she unleashes this brutal onslaught, the world’s boundaries will shrink ever so slightly – her minions will regroup and retreat.
As a result, the combat becomes even more thrilling, since once she executes her initial spear attack, she’s unable to land any additional hits. Despite these limitations, she will continue to utilize every ability at her disposal, including melee attacks, lightning daggers, fire and chaos bombardments, and poisonous projectiles.
As the stakes escalate, dodging becomes an increasingly crucial tactic, as she refuses to relinquish her pursuit of you or permit any further attempts at evasion. Strive to maintain a healthy distance from her while utilizing your expertise to the fullest extent possible. A single misjudged dodge can leave you vulnerable to a hail of attacks, obliging you to hastily retreat and recover from the damage by using one of your available flasks. To preserve the remaining 5% of her overall wellness, one must be prepared to face the inevitable challenges that arise as the world shrinks and potential threats become increasingly difficult to avoid.
The assaults don’t follow a predetermined sequence. She employs a variety of tactics in quick succession, alternating between consecutive bombardments, relentless melee assaults, and fluid transitions between the two. To effectively anticipate and counter attacks, you must thoroughly familiarize yourself with the telltale signs that precede each assault. She’ll execute a spear attack from a hovering position when her health dips to around 30%.
As her vitality dwindles to just 5%, she’ll unleash her spear attack with increased ferocity. Despite the challenges, the world will remain vast and complex, offering a glimmer of hope. You’re forced to endure the attack until your opponent starts fighting back on the ground again, allowing you to resume dealing damage.
After defeating Viper Naputazi, you are now poised to tackle the formidable Merciless problem, ultimately reaching the endgame.